Pharmaceutical-Grade Coenzyme Supply
Lyophilized NAD+ (nicotinamide adenine dinucleotide, CAS 53-84-9) in 500 mg and 1000 mg vials. Manufactured in the United States, verified at ≥99% purity by HPLC, and shipped with a lot-matched Certificate of Analysis on every order.
The Molecule
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell. It functions as the primary electron carrier in cellular respiration, shuttling electrons between the oxidized (NAD+) and reduced (NADH) states to drive ATP production in the mitochondria.
NAD+ is the electron acceptor in glycolysis, the citric acid cycle, and fatty acid oxidation. Without an adequate NAD+ pool, the electron transport chain cannot sustain ATP synthesis — which is why the molecule is studied so heavily in mitochondrial-function research.
NAD+ is the required substrate for the PARP family of DNA-repair enzymes and for the sirtuins (SIRT1–SIRT7), a class of NAD+-dependent deacetylases. Both enzyme families consume NAD+ directly, linking the cellular NAD+ pool to genomic maintenance pathways.
Tissue NAD+ concentrations decline measurably with age across multiple mammalian models. That observation is the basis for the substantial body of published research examining NAD+ in the context of mitochondrial function, metabolic regulation, and cellular ageing.
NAD+ is a coenzyme, not a peptide. This is a common point of confusion, because NAD+ is frequently stocked alongside peptide compounds by the same suppliers. Structurally they are unrelated: peptides are short chains of amino acids joined by peptide bonds, whereas NAD+ is a dinucleotide — two nucleotides (one carrying adenine, one carrying nicotinamide) joined through a pair of bridging phosphate groups. Molecular formula C₂₁H₂₇N₇O₁₄P₂, molecular weight 663.43 g/mol.
Product Data
Every vial is lyophilized under controlled conditions and sealed for clinical reconstitution. Full analytical documentation is released with each lot.
| Specification | Value |
|---|---|
| Compound | NAD+ (β-Nicotinamide adenine dinucleotide) |
| CAS number | 53-84-9 |
| Molecular formula | C₂₁H₂₇N₇O₁₄P₂ |
| Molecular weight | 663.43 g/mol |
| Purity | ≥99% by HPLC, third-party verified |
| Presentation | Lyophilized powder, sealed vial |
| Vial sizes | 500 mg · 1000 mg |
| Storage (lyophilized) | −20 °C, protected from light |
| Storage (reconstituted) | 2–8 °C |
| Documentation | Lot-matched Certificate of Analysis |
| Country of manufacture | United States |
| Availability | Licensed physicians, clinics and healthcare practices |
Bacteriostatic water, reconstitution solution, and complete reconstitution kits are available to order alongside vials so your practice receives everything in a single shipment.
Each shipment includes the Certificate of Analysis for the specific lot supplied — not a representative or historical document. HPLC chromatograms available on request.
Vials ship insulated with temperature control appropriate to transit time, so material arrives within its specified storage range and ready for your clinic's intake process.
Clinical Context
Practitioners evaluating NAD+ generally encounter three distinct delivery routes, which differ substantially in pharmacokinetics, chair time, and practice workflow. The route your protocol calls for determines the vial format and reconstitution volume you should be ordering.
Mitova Bioscience supplies the lyophilized NAD+ raw material itself. We do not supply protocols, dosing schedules, or clinical guidance — determination of route, dose and patient suitability rests entirely with the treating licensed practitioner.
Reconstituted NAD+ administered subcutaneously in small divided volumes. Short administration time; the format most commonly associated with at-home patient protocols dispensed under practitioner supervision.
NAD+ diluted into a carrier solution and infused over an extended period. The dominant format in IV therapy and infusion clinics, and the route most associated with the "NAD+ IV therapy" service category.
NMN and NR are oral precursor compounds that the body converts toward NAD+ through the salvage pathway. Distinct from injectable NAD+ in both bioavailability profile and regulatory classification.
NAD+ is not an FDA-approved drug product, and no statement on this page should be read as a claim that NAD+ diagnoses, treats, cures or prevents any disease. Material supplied by Mitova Bioscience is sold exclusively to licensed medical professionals, clinics and healthcare practices for use within the scope of their license and applicable state and federal law. It is not sold to consumers and is not for personal use.
Wholesale Access
Accounts are opened for licensed practitioners and the practices they operate under. Submit your credential details and we will verify your license and return current wholesale pricing, tier breaks and lead times.
Verification typically completes within one business day. You will not be added to any marketing list without opting in below.
Common Questions
NAD+ injections deliver nicotinamide adenine dinucleotide parenterally — most often subcutaneously or by intravenous infusion — rather than orally. The lyophilized powder is reconstituted with bacteriostatic water or an appropriate solution immediately before administration. The injectable route bypasses first-pass metabolism, which is the principal pharmacokinetic difference from oral NAD+ precursor supplements.
No. NAD+ is a dinucleotide coenzyme, not a peptide. Peptides are chains of amino acids linked by peptide bonds; NAD+ consists of two nucleotides — one containing adenine, one containing nicotinamide — joined by bridging phosphate groups, with the formula C₂₁H₂₇N₇O₁₄P₂. The confusion is common simply because NAD+ is often stocked alongside peptides by the same suppliers.
They refer to the same molecule in different oxidation states. "NAD" is the general name; the plus sign denotes the oxidized form, which carries a positive charge on its nicotinamide ring and is the form that accepts electrons. The reduced form is written NADH. Cells continuously cycle between the two, and the NAD+/NADH ratio is itself a meaningful metabolic signal.
Mitova Bioscience does not provide dosing guidance. Dose, route, frequency and patient suitability are clinical determinations that rest entirely with the treating licensed practitioner, based on their own judgement and the published literature. We supply verified raw material with full analytical documentation so practitioners can make those decisions from a known starting point.
Lyophilized vials are stored at −20 °C and protected from light. Reconstitution is performed with bacteriostatic water or another appropriate solution, directed gently down the vial wall rather than injected directly onto the powder. Once reconstituted, material is held at 2–8 °C. Reconstitution kits, bacteriostatic water and reconstitution solution can be added to any order.
No. Mitova Bioscience supplies licensed physicians, clinics and healthcare practices only. Every account is license-verified before pricing is released and before any order is fulfilled. We do not sell to consumers under any circumstances.
Every shipment includes the Certificate of Analysis matched to the specific lot supplied, confirming identity and ≥99% purity by HPLC. The full chromatogram and third-party verification report are available on request for any lot we have shipped you.
No. NAD+ is not an FDA-approved drug product. It is supplied to licensed practitioners for use within the scope of their license and applicable law. Nothing on this page constitutes a claim that NAD+ diagnoses, treats, cures or prevents any disease, and nothing here should be construed as medical advice.